Disease: Myeloproliferative disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZNRD2 O60232 zinc ribbon domain containing 2 1.8E-07 0.443 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ULK1 O75385 unc-51 like autophagy activating kinase 1 Kinase 0.99 0.564 0.769
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TMED7-TICAM2 Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 2.6E-03 0.438 0.769
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TICAM2 Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 2.6E-03 0.438 0.769
THPO P40225 thrombopoietin 0.20 0.513 0.692
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SOCS3 O14543 suppressor of cytokine signaling 3 Enzyme modulator 0.75 0.434 0.808
SOCS2 O14508 suppressor of cytokine signaling 2 Enzyme modulator 0.63 0.560 0.731
SOCS1 O15524 suppressor of cytokine signaling 1 Enzyme modulator 0.59 0.445 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692